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The submitted manuscript is the authors original work, has not been previously published, and is not under consideration for publication elsewhere

This dramatic increase in the risk of premature mortality is due to the repeated exposure of smokers to the thousands of toxic and carcinogenic substances that are generated during the combustion of tobacco leaves (polycyclic aromatic hydrocarbons and nitrosamines, among others)

The smallest effect of standardization was observed among those who had never vaped or smoked: 93% of those in the standardized group reported no interest compared with just over 91% of those in the branded group